BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and S
Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-discipli
| Agency | National Institutes of Health |
|---|---|
| Status | Posted |
| Opportunity number | RFA-DC-27-004 |
| Posted date | 05/04/2026 |
| Application deadline | Feb 11, 2027 12:00:00 AM EST |
| Award ceiling | 700,000 |
| Award floor | none |
| Estimated total funding | 6,000,000 |
| Expected number of awards | 5 |
| Who can apply | Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
| Assistance Listing (CFDA) | 93.242, 93.173, 93.286, 93.866, 93.273, 93.279, 93.865, 93.853, 93.213, 93.867 |
| Description | Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-disciplinary teams, to understand how dynamic activity of single cells and ensembles of neurons in spatially organized networks gives rise to the internal states we experience as sensations, perceptions, emotions, thoughts, and memories, and to observable motor and social behaviors. The research should be proposed as exploratory research and planning activities to establish feasibility and early-stage development that, if successful, would support, enable, and/or lay the groundwork f |
| Agency contact | BRAINeROH@ninds.nih.gov |
| Official listing | https://www.grants.gov/search-results-detail/359649 |