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Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG

The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs. This includes preclinical and clin

AgencyNational Institutes of Health
StatusPosted
Opportunity numberPAR-25-446
Posted date09/10/2025
Application deadlineAug 21, 2028 12:00:00 AM EDT
Award ceiling3,000,000
Award floornone
Who can applyOther Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.
Assistance Listing (CFDA)93.279
DescriptionThe purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. This NOFO will utilize the UG3/UH3 activity code.
Agency contactgrantsinfo@nih.gov
Official listinghttps://www.grants.gov/search-results-detail/358937

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