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DoW Amyotrophic Lateral Sclerosis Research Program, Therapeutic Development Award

Summary: The fiscal year 2026 (FY26) Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Development Award (TDA) supports research ranging from preclinical validation of therapeutic leads through U.S. Food and Drug Administration (FDA) Investigational New Drug (IND)-enabling studies. The proposed studies

AgencyDept. of the Army -- USAMRAA
StatusPosted
Opportunity numberHT942526ALSRPTDA
Posted date05/04/2026
Application deadlineSep 30, 2026 12:00:00 AM EDT
Award ceilingnone
Award floornone
Estimated total funding12,000,000
Expected number of awards6
Assistance Listing (CFDA)12.420
DescriptionSummary: The fiscal year 2026 (FY26) Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Development Award (TDA) supports research ranging from preclinical validation of therapeutic leads through U.S. Food and Drug Administration (FDA) Investigational New Drug (IND)-enabling studies. The proposed studies are expected to be empirical in nature and product-driven. Applicants with limited amyotrophic lateral sclerosis (ALS) experience are strongly encouraged to include collaborators with substantial experience in the relevant ALS model systems, endpoints and pathophysiology. Applications supported by this award must begin with lead compounds in hand and must already demonstrate proof-of-concept efficacy data in at least one appropriate preclinical model system of ALS, including
Agency contacthelp@eBRAP.org
Official listinghttps://www.grants.gov/search-results-detail/362196

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