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INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support

AgencyNational Institutes of Health
StatusPosted
Opportunity numberRFA-OD-27-004
Posted date05/12/2026
Application deadlineJun 15, 2028 12:00:00 AM EDT
Award ceiling500,000
Award floornone
Estimated total funding3,000,000
Expected number of awards4
Who can applyRefer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Assistance Listing (CFDA)93.867, 93.310, 93.846, 93.855, 93.395, 93.847, 93.351, 93.838, 93.866, 93.837, 93.121, 93.233, 93.839, 93.865, 93.879, 93.350, 93.173, 93.242, 93.840
DescriptionThe NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects mus
Agency contactDownSyndromeINCLUDE@mail.nih.gov
Official listinghttps://www.grants.gov/search-results-detail/360654

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