Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcome
The National Institute of Mental Health intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research to identify modifiable targets and mechanisms to alleviate clinically relevant central nervous system (CNS) complications in people with HIV. This NOFO supports research that leverages
| Agency | National Institutes of Health |
|---|---|
| Status | Forecasted |
| Opportunity number | FOR-MH-26-165 |
| Posted date | 06/09/2025 |
| Estimated total funding | 3,000,000 |
| Expected number of awards | 6 |
| Assistance Listing (CFDA) | 93.242 |
| Description | The National Institute of Mental Health intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research to identify modifiable targets and mechanisms to alleviate clinically relevant central nervous system (CNS) complications in people with HIV. This NOFO supports research that leverages patient derived data and innovative model platforms to identify and validate novel therapeutic targets underlying CNS complications. Building on advances in systems biology, this initiative seeks to identify modifiable mechanisms contributing to CNS dysfunction through clinical studies or pre-clinical model systems. The ultimate goal is to accelerate the development of effective, mechanism-based interventions that address the multifactorial and heterogeneous nature of CNS com |
| Agency contact | vasudev.rao@nih.gov |
| Official listing | https://www.grants.gov/search-results-detail/359657 |