NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System
The NIH Blueprint (a consortium of NIH Institutes that support neuroscience research) seeks to advance its mission by supporting the development, optimization, validation, and application of germline and somatic transgenic and gene-editing approaches in experimental systems modeling key features of human brain anatomy,
| Agency | National Institutes of Health |
|---|---|
| Status | Forecasted |
| Opportunity number | RFA-DA-27-012 |
| Posted date | 05/07/2026 |
| Award ceiling | 1,200,000 |
| Estimated total funding | 7,200,000 |
| Expected number of awards | 4 |
| Who can apply | Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions). |
| Assistance Listing (CFDA) | 93.279 |
| Description | The NIH Blueprint (a consortium of NIH Institutes that support neuroscience research) seeks to advance its mission by supporting the development, optimization, validation, and application of germline and somatic transgenic and gene-editing approaches in experimental systems modeling key features of human brain anatomy, circuitry, cognition, behavior, and lifespan. This initiative will build on the previously supported marmoset gene-editing infrastructure, by integrating New Approach Methodologies (NAMs) with other models, to advance understanding of human brain function and disease, including human-derived NAMs for cross-species comparisons across development. Many mechanisms of complex conditions, such as autism spectrum disorders, schizophrenia, and other behavioral/developmental disorde |
| Agency contact | NIDA_GED_Program@nida.nih.gov |
| Official listing | https://www.grants.gov/search-results-detail/362313 |