NIH Director’s Transformative Research Awards (R01 Clinical Trial Optional)
The NIH Director’s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or de
| Agency | National Institutes of Health |
|---|---|
| Status | Forecasted |
| Opportunity number | RFA-RM-26-003 |
| Posted date | 01/06/2026 |
| Estimated total funding | 8,000,000 |
| Expected number of awards | 7 |
| Who can apply | Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government, excluding the NIH Intramural Research Program (NIH IRP);U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions). |
| Assistance Listing (CFDA) | 93.310 |
| Description | The NIH Director’s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Director’s Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund . |
| Agency contact | Transformative_Awards@mail.nih.gov |
| Official listing | https://www.grants.gov/search-results-detail/361084 |