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Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unm

The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs. Through the support of natural history studies with high quality and interpretable data elements, FDA expects to

AgencyFood and Drug Administration
StatusPosted
Opportunity numberRFA-FD-25-017
Posted date07/11/2025
Application deadlineFeb 08, 2028 12:00:00 AM EST
Award ceiling600,000
Award floor0
Who can applyEligible OrganizationsHigher Education InstitutionsPublic/State Controlled Institutions of Higher EducationPrivate Institutions of Higher EducationNonprofits Other Than Institutions of Higher EducationNonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)For-Profit OrganizationsSmall BusinessesFor-Profit Organizations (Other than Small Businesses)Local GovernmentsState GovernmentsCoun
Assistance Listing (CFDA)93.103
DescriptionThe purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs. Through the support of natural history studies with high quality and interpretable data elements, FDA expects to address critical knowledge gaps, remove major barriers to progress in the field, exert a significant and broad impact on a specific rare disease or multiple rare diseases with similar pathophysiology, and facilitate rare disease product development.
Agency contactKimberly.Pendleton@fda.hhs.gov
Official listinghttps://www.grants.gov/search-results-detail/360007

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