Selective Precision Targeting (SPoT)
The National Center for Advancing Translational Science (NCATS) seeks to advance its mission by establishing a new initiative called Selective Precision Targeting (SPoT) to determine a mechanism for precise and on-target therapeutic drug delivery to specific hard-to-reach locations within the human body using microphys
| Agency | National Institutes of Health |
|---|---|
| Status | Forecasted |
| Opportunity number | FOR-TR-27-003 |
| Posted date | 06/27/2025 |
| Estimated total funding | 1,500,000 |
| Expected number of awards | 5 |
| Assistance Listing (CFDA) | 93.350 |
| Description | The National Center for Advancing Translational Science (NCATS) seeks to advance its mission by establishing a new initiative called Selective Precision Targeting (SPoT) to determine a mechanism for precise and on-target therapeutic drug delivery to specific hard-to-reach locations within the human body using microphysiological systems (MPS). Targeted drug-delivery systems, including engineered nanoparticles, extracellular vesicles or focused ultrasound, are methods for delivering medications to a specific area of the body (organ, tissue, or cell) to increase the concentration of the drug in that area. Hard-to-reach locations in the body include the blood–brain barrier, central nervous system, placenta, retina, or a tumor. More specifically, the initiative goals are to: Optimize specific t |
| Agency contact | passley.hargrove@nih.gov |
| Official listing | https://www.grants.gov/search-results-detail/359852 |