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Cellular mechanisms of neuronal dysfunction in addiction and neurodegeneration — Brandon Harvey (NATIONAL INSTITUTE ON DRUG ABUSE)

We identified a phenomenon in cell biology by which decreases in endoplasmic reticulum calcium levels leads to the secretion of resident proteins of the ER lumen. We show that the cell upregulates KDE

Project titleCellular mechanisms of neuronal dysfunction in addiction and neurodegeneration
Project number1ZIADA000618-08
PI nameBrandon Harvey
InstitutionNATIONAL INSTITUTE ON DRUG ABUSE
Funding mechanismZIA
AgencyNIDA
Award amount$2.77M
Fiscal year2024
AbstractWe identified a phenomenon in cell biology by which decreases in endoplasmic reticulum calcium levels leads to the secretion of resident proteins of the ER lumen. We show that the cell upregulates KDE
Key terms<2-Bromo-alpha-ergocryptine><2-Bromo-alpha-ergokryptine><2-Bromoergocryptine><2-Bromoergokryptine><3

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