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Discovering Small Molecule Activators of Stress-Responsive Signaling — JEFFERY W KELLY (SCRIPPS RESEARCH INSTITUTE, THE)

PROJECT SUMMARY Endoplasmic reticulum (ER) stress is implicated in the onset and pathogenesis of diverse age-related diseases, including many neurodegenerative disorders. In these diseases, ER stress

Project titleDiscovering Small Molecule Activators of Stress-Responsive Signaling
Project number2RF1AG046495-11
PI nameJEFFERY W KELLY
InstitutionSCRIPPS RESEARCH INSTITUTE, THE
Funding mechanismRF1
AgencyNIA
Award amount$2.62M
Fiscal year2023
Project start2013-04-01T00:00:00
Project end2026-03-31T00:00:00
AbstractPROJECT SUMMARY Endoplasmic reticulum (ER) stress is implicated in the onset and pathogenesis of diverse age-related diseases, including many neurodegenerative disorders. In these diseases, ER stress
Key terms<AD dementia><AD model><ATF6><ATF6 gene><Activating Transcription Factor 6><Acute Disease><Age><Agin

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