Exploiting DNA Replicative Stress for Novel Small Cell Lung Cancer Therapies — Anish Thomas (DIVISION OF BASIC SCIENCES - NCI)
1. Targeting replication stress in cancer: Stalled replication forks activate ataxia telangiectasia and Rad3-related kinase (ATR), which subsequently phosphorylate downstream kinases including CHK1. T
| Project title | Exploiting DNA Replicative Stress for Novel Small Cell Lung Cancer Therapies |
|---|---|
| Project number | 1ZIABC011793-06 |
| PI name | Anish Thomas |
| Institution | DIVISION OF BASIC SCIENCES - NCI |
| Funding mechanism | ZIA |
| Agency | NCI |
| Award amount | $2.22M |
| Fiscal year | 2023 |
| Abstract | 1. Targeting replication stress in cancer: Stalled replication forks activate ataxia telangiectasia and Rad3-related kinase (ATR), which subsequently phosphorylate downstream kinases including CHK1. T |
| Key terms | <ACSL1><ACSL1 Gene><ASCL1><ASCL1 gene><ASCL1 protein><ASH1><ATR gene><ATR protein><ATR protein kinas |
$799/mo
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