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Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amy — Suma Babu (MASSACHUSETTS GE

ALS is a lethal neurodegenerative disease accelerated by neuroinflammation. Current FDA-approved therapies have modest benefits and do not address inflammation. To address this, RAPA Therapeutics, LLC

Project titleIntermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amy
Project number1U01NS136020-01
PI nameSuma Babu
InstitutionMASSACHUSETTS GENERAL HOSPITAL
Funding mechanismU01
AgencyNINDS
Award amount$11.20M
Fiscal year2023
Project start2023-09-25T00:00:00
Project end2026-08-31T00:00:00
AbstractALS is a lethal neurodegenerative disease accelerated by neuroinflammation. Current FDA-approved therapies have modest benefits and do not address inflammation. To address this, RAPA Therapeutics, LLC
Key terms<(TNF)-α><2-Amino-6-trifluoromethoxybenzothiazole><3-10C><ALS therapy><ALS treatment><AMCF-I><Academ

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