Allopurinol
Allopurinol is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Allopurinol; Generic name: ALLOPURINOL; Drug class: Xanthine Oxidase Inhibitor [EPC].
| Brand name | Allopurinol |
|---|---|
| Generic name | ALLOPURINOL |
| Drug class | Xanthine Oxidase Inhibitor [EPC] |
| Manufacturer | Harman Finochem Limited |
| Used for | 1. INDICATIONS AND USAGE Allopurinol tablets are indicated for: • The management of adults with signs and symptoms of primary or secondary gout (acute attacks, tophi, joint destruction, uric acid lithiasis, and/or nephropathy) • The management of adult and pediatric patients with leukemia, lymphoma and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels • The management of adult patients with recurrent calcium oxalate calculi whose daily uric acid excretion exceeds 800 mg/day in male patients and 750 mg/day in female patients, despite lifestyle changes (such as reduction of dietary sodium, non-dairy animal protein, oxylate r |
| Dosage | 2. DOSAGE AND ADMINISTRATION • Gout : Prior to initiating treatment assess serum uric acid level, complete blood count, chemistry panel, liver and kidney function tests. Prophylactic treatment for gout flares is recommended. (2.1, 2.2) - Patients with normal kidney function: Initial dosage is 100 mg orally daily. Increase by 100 mg weekly increments until serum uric acid of 6 mg/dl or less is reached (maximum 800 mg daily). (2.3) - Patients with impaired kidney function: The initial dosage is 50 |
| Active ingredient(s) | ALLOPURINOL |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0780dc78-d287-d5db-e063-6294a90aa1dd |