Amiloride Hydrochloride
Amiloride Hydrochloride is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Amiloride Hydrochloride; Generic name: AMILORIDE HYDROCHLORIDE; Manufacturer: Bryant Ranch Prepack.
| Brand name | Amiloride Hydrochloride |
|---|---|
| Generic name | AMILORIDE HYDROCHLORIDE |
| Manufacturer | Bryant Ranch Prepack |
| Used for | INDICATIONS AND USAGE Amiloride HCl is indicated as adjunctive treatment with thiazide diuretics or other kaliureticdiuretic agents in congestive heart failure or hypertension to: help restore normal serum potassium levels in patients who develop hypokalemia on the kaliuretic diuretic. prevent development of hypokalemia in patients who would be exposed to particular risk if hypokalemia were to develop, e.g., digitalized patients or patients with significant cardiac arrhythmias. The use of potassium-conserving agents is often unnecessary in patients receiving diuretics for uncomplicated essential hypertension when such patients have a normal diet. Amiloride HCl has little additive diuretic or |
| Dosage | DOSAGE AND ADMINISTRATION Amiloride HCl should be administered with food. Amiloride HCl, one 5 mg tablet daily, should be added to the usual antihypertensive or diuretic dosage of a kaliuretic diuretic. The dosage may be increased to 10 mg per day, if necessary. More than two 5 mg tablets of amiloride HCl daily usually are not needed, and there is little controlled experience with such doses. If persistent hypokalemia is documented with 10 mg, the dose can be increased to 15 mg, then 20 mg, with |
| Warnings | WARNINGS Hyperkalemia Like other potassium-conserving agents, amiloride may cause hyperkalemia (serum potassium levels greater than 5.5 mEq per liter) which, if uncorrected, is potentially fatal. Hyperkalemia occurs commonly (about 10%) when amiloride is used without a kaliuretic diuretic. This incidence is greater in patients with renal impairment, diabetes mellitus (with or without recognized renal insufficiency), and in the elderly. When amiloride is used concomitantly with a thiazide diureti |
| Active ingredient(s) | AMILORIDE HYDROCHLORIDE ANHYDROUS |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=18d551a9-ffc7-4b14-adbd-92d84aa8e966 |