Amphotericin B
Amphotericin B is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Amphotericin B; Generic name: AMPHOTERICIN B; Drug class: Lipid-based Polyene Antifungal [EPC].
| Brand name | Amphotericin B |
|---|---|
| Generic name | AMPHOTERICIN B |
| Drug class | Lipid-based Polyene Antifungal [EPC] |
| Manufacturer | Sun Pharmaceutical Industries, Inc. |
| Used for | INDICATIONS AND USAGE Amphotericin B liposome for injection is indicated for the following: Empirical therapy for presumed fungal infection in febrile, neutropenic patients. Treatment of Cryptococcal Meningitis in HIV-infected patients (see DESCRIPTION OF CLINICAL STUDIES) . Treatment of patients with Aspergillus species, Candida species and/or Cryptococcus species infections (see above for the treatment of Cryptococcal Meningitis) refractory to amphotericin B deoxycholate, or in patients where renal impairment or unacceptable toxicity precludes the use of amphotericin B deoxycholate. Treatment of visceral leishmaniasis. In immunocompromised patients with visceral leishmaniasis treated with |
| Dosage | DOSAGE AND ADMINISTRATION Amphotericin B liposome for injection is not interchangeable or substitutable on a mg per mg basis with other amphotericin B products. Different amphotericin B products are not equivalent in terms of pharmacodynamics, pharmacokinetics and dosing. Amphotericin B liposome for injection should be administered by intravenous infusion, using a controlled infusion device, over a period of approximately 120 minutes. An in-line membrane filter may be used for the intravenous in |
| Warnings | WARNINGS Anaphylaxis has been reported with amphotericin B deoxycholate and other amphotericin B-containing drugs, including amphotericin B liposome for injection. If a severe anaphylactic reaction occurs, the infusion should be immediately discontinued and the patient should not receive further infusions of amphotericin B liposome for injection. |
| Active ingredient(s) | AMPHOTERICIN B |
| Route | INTRAVENOUS |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=02aadef1-390b-4270-b56d-33452eb89dde |