Avalide (IRBESARTAN AND HYDROCHLOROTHIAZIDE)
Avalide (IRBESARTAN AND HYDROCHLOROTHIAZIDE) is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Avalide; Generic name: IRBESARTAN AND HYDROCHLOROTHIAZIDE; Drug class: Angiotensin 2 Receptor Blocker [EPC].
| Brand name | Avalide |
|---|---|
| Generic name | IRBESARTAN AND HYDROCHLOROTHIAZIDE |
| Drug class | Angiotensin 2 Receptor Blocker [EPC] |
| Manufacturer | Sanofi-Aventis U.S. LLC |
| Used for | 1 INDICATIONS AND USAGE AVALIDE ® (irbesartan and hydrochlorothiazide) tablets are indicated for the treatment of hypertension. AVALIDE may be used in patients whose blood pressure is not adequately controlled on monotherapy. AVALIDE may also be used as initial therapy in patients who are likely to need multiple drugs to achieve their blood pressure goals. The choice of AVALIDE as initial therapy for hypertension should be based on an assessment of potential benefits and risks. Patients with stage 2 (moderate or severe) hypertension are at relatively high risk for cardiovascular events (such as strokes, heart attacks, and heart failure), kidney failure, and vision problems, so prompt treatme |
| Dosage | 2 DOSAGE AND ADMINISTRATION General Considerations Maximum effects within 2 to 4 weeks after dose change. ( 2.1 ) Renal impairment: Not recommended for patients with severe renal impairment (creatinine clearance <30 mL/min). ( 2.1 , 5.8 ) Hypertension Initiate with 150/12.5 mg. Titrate to 300/12.5 mg then 300/25 mg if needed. ( 2.2 ) Replacement therapy: May be substituted for titrated components. ( 2.3 ) 2.1 General Considerations The side effects of irbesartan are generally rare and apparently |
| Warnings | WARNING: FETAL TOXICITY When pregnancy is detected, discontinue AVALIDE as soon as possible [see Warnings and Precautions (5.1) and Use in Specific Populations (8.1) ] . Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus [see Warnings and Precautions (5.1) and Use in Specific Populations (8.1) ] . WARNING: FETAL TOXICITY See full prescribing information for complete boxed warning. When pregnancy is detected, discontinue AVALIDE as soon as p |
| Active ingredient(s) | HYDROCHLOROTHIAZIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0d91895e-c869-4b33-9b83-d55c1ad6317e |