Baclofen (Intrathecal) (BACLOFEN)
Baclofen (Intrathecal) (BACLOFEN) is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Baclofen (Intrathecal); Generic name: BACLOFEN; Drug class: gamma-Aminobutyric Acid-ergic Agonist [EPC].
| Brand name | Baclofen (Intrathecal) |
|---|---|
| Generic name | BACLOFEN |
| Drug class | gamma-Aminobutyric Acid-ergic Agonist [EPC] |
| Manufacturer | MAIA Pharmaceuticals, Inc. |
| Used for | INDICATIONS AND USAGE Baclofen injection (intrathecal) is indicated for use in the management of severe spasticity. Patients should first respond to a screening dose of intrathecal baclofen prior to consideration for long term infusion via an implantable pump. For spasticity of spinal cord origin, chronic infusion of baclofen injection (intrathecal) via an implantable pump should be reserved for patients unresponsive to oral baclofen therapy, or those who experience intolerable CNS side effects at effective doses. Patients with spasticity due to traumatic brain injury should wait at least one year after the injury before consideration of long term intrathecal baclofen therapy. Baclofen injec |
| Dosage | DOSAGE AND ADMINISTRATION Refer to the manufacturer’s manual for the implantable pump approved for intrathecal infusion for specific instructions and precautions for programming the pump and/or refilling the reservoir. There are various pumps with varying reservoir volumes and there are various refill kits available. It is important to be familiar with all of these products in order to select the appropriate refill kit for the particular pump in use. Screening Phase: Prior to pump implantation a |
| Warnings | WARNINGS Baclofen injection (intrathecal) is for use in single bolus intrathecal injections (via a catheter placed in the lumbar intrathecal space or injection by lumbar puncture) and in implantable pumps approved by the FDA specifically for the intrathecal administration of baclofen. Because of the possibility of potentially life- threatening CNS depression, cardiovascular collapse, and/or respiratory failure, physicians must be adequately trained and educated in chronic intrathecal infusion th |
| Active ingredient(s) | BACLOFEN |
| Route | INTRATHECAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=11ba5575-a856-414a-89f8-17f3a01de55b |