bupropion Hydrochloride
bupropion Hydrochloride is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: bupropion Hydrochloride; Generic name: BUPROPION HYDROCHLORIDE; Manufacturer: Bryant Ranch Prepack.
| Brand name | bupropion Hydrochloride |
|---|---|
| Generic name | BUPROPION HYDROCHLORIDE |
| Manufacturer | Bryant Ranch Prepack |
| Used for | 1 INDICATIONS AND USAGE Bupropion hydrochloride tablets are an aminoketone antidepressant, indicated for the treatment of major depressive disorder (MDD). ( 1 ) Bupropion hydrochloride tablets are indicated for the treatment of major depressive disorder (MDD), as defined by the Diagnostic and Statistical Manual (DSM). The efficacy of bupropion hydrochloride tablets in the treatment of a major depressive episode was established in two 4-week controlled inpatient trials and one 6-week controlled outpatient trial of adult subjects with MDD [see Clinical Studies ( 14) ]. |
| Dosage | 2 DOSAGE AND ADMINISTRATION Starting dose: 200 mg/day given as 100 mg twice daily ( 2.1 ) General: Increase dose gradually to reduce seizure risk. ( 2.1 , 5.3 ) After 3 days, may increase the dose to 300 mg/day, given as 100 mg 3 times daily at an interval of at least 6 hours between doses. ( 2.1 ) Usual target dose: 300 mg/day as 100 mg 3 times daily. ( 2.1 ) Maximum dose: 450 mg/day given as 150 mg 3 times daily. ( 2.1 ) Periodically reassess the dose and need for maintenance treatment. ( 2.1 |
| Warnings | WARNING: SUICIDAL THOUGHTS AND BEHAVIORS WARNING: SUICIDAL THOUGHTS AND BEHAVIORS See full prescribing information for complete boxed warning. Increased risk of suicidal thinking and behavior in children, adolescents, and young adults taking antidepressants. ( 5.1 ) Monitor for worsening and emergence of suicidal thoughts and behaviors. ( 5.1 ) SUICIDALITY AND ANTIDEPRESSANT DRUGS Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in s |
| Active ingredient(s) | BUPROPION HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=144379e1-93b7-41c1-bc3a-7bdec5afa309 |