Bupropion Hydrochloride SR (BUPROPION HYDROCHLORIDE)
Bupropion Hydrochloride SR (BUPROPION HYDROCHLORIDE) is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Bupropion Hydrochloride SR; Generic name: BUPROPION HYDROCHLORIDE; Manufacturer: Proficient Rx LP.
| Brand name | Bupropion Hydrochloride SR |
|---|---|
| Generic name | BUPROPION HYDROCHLORIDE |
| Manufacturer | Proficient Rx LP |
| Used for | 1 INDICATIONS AND USAGE Bupropion hydrochloride extended-release tablets (SR) is indicated for the treatment of major depressive disorder (MDD), as defined by the Diagnostic and Statistical Manual (DSM). The efficacy of bupropion in the treatment of a major depressive episode was established in two 4-week controlled inpatient trials and one 6-week controlled outpatient trial of adult subjects with MDD [see Clinical Studies ( 14 )] . The efficacy of bupropion hydrochloride extended-release tablets (SR) in maintaining an antidepressant response for up to 44 weeks following 8 weeks of acute treatment was demonstrated in a placebo-controlled trial [see Clinical Studies ( 14 )] . • Bupropion hydr |
| Dosage | 2 DOSAGE AND ADMINISTRATION • Starting dose: 150 mg/day ( 2.1 ) • General: Increase dose gradually to reduce seizure risk. ( 2.1 , 5.3 ) • After 3 days, may increase the dose to 300 mg/day, given as 150 mg twice daily at an interval of at least 8 hours. ( 2.1 ) • Usual target dose: 300 mg/day as 150 mg twice daily. ( 2.1 ) • Maximum dose: 400 mg/day, given as 200 mg twice daily, for patients not responding to 300 mg/day. ( 2.1 ) • Periodically reassess the dose and need for maintenance treatment |
| Warnings | WARNING: SUICIDAL THOUGHTS AND BEHAVIORS SUICIDALITY AND ANTIDEPRESSANT DRUGS Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term trials. These trials did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in subjects over age 24; there was a reduction in risk with antidepressant use in subjects aged 65 and older [see Warnings and Precautions ( 5.1 )] . In patients of all ages who ar |
| Active ingredient(s) | BUPROPION HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1094ff8e-f5a5-4a72-8bf9-25e68f5c964a |