CINACALCET
CINACALCET is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: CINACALCET; Generic name: CINACALCET; Manufacturer: EXELAN PHARMACEUTICALS INC..
| Brand name | CINACALCET |
|---|---|
| Generic name | CINACALCET |
| Manufacturer | EXELAN PHARMACEUTICALS INC. |
| Used for | 1 INDICATIONS AND USAGE Cinacalcet hydrochloride is a calcium-sensing receptor agonist indicated for: Secondary Hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on dialysis. ( 1.1 ) Limitations of Use: Cinacalcet hydrochloride tablets are not indicated for use in patients with CKD who are not on dialysis. Hypercalcemia in adult patients with Parathyroid Carcinoma (PC). ( 1.2 ) Severe hypercalcemia in adult patients with primary HPT who are unable to undergo parathyroidectomy. ( 1.3 ) 1.1 Secondary Hyperparathyroidism Cinacalcet hydrochloride tablets are indicated for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney diseas |
| Dosage | 2 DOSAGE AND ADMINISTRATION Cinacalcet hydrochloride tablets should be taken with food or shortly after a meal ( 2.1 ). Tablets should always be taken whole and not divided ( 2.1 ) Secondary HPT in patients with CKD on dialysis ( 2.2 ): Starting dose is 30 mg once daily. Titrate dose no more frequently than every 2 to 4 weeks through sequential doses of 30, 60, 90, 120, and 180 mg once daily as necessary to achieve targeted intact parathyroid hormone (iPTH) levels. iPTH levels should be measured |
| Active ingredient(s) | CINACALCET HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=04a978cb-d57b-4f1e-ba14-316b6f9abe33 |