Clofarabine
Clofarabine is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Clofarabine; Generic name: CLOFARABINE; Drug class: Nucleoside Metabolic Inhibitor [EPC].
| Brand name | Clofarabine |
|---|---|
| Generic name | CLOFARABINE |
| Drug class | Nucleoside Metabolic Inhibitor [EPC] |
| Manufacturer | Dr.Reddy's Laboratories Inc |
| Used for | 1 INDICATIONS AND USAGE Clofarabine injection is indicated for the treatment of pediatric patients 1 to 21 years old with relapsed or refractory acute lymphoblastic leukemia after at least two prior regimens. Clofarabine injection is a nucleoside metabolic inhibitor indicated for the treatment of pediatric patients 1 to 21 years old with relapsed or refractory acute lymphoblastic leukemia after at least two prior regimens. ( 1 ) |
| Dosage | 2 DOSAGE AND ADMINISTRATION Administer the recommended pediatric dose of 52 mg/m 2 as an intravenous infusion over 2 hours daily for 5 consecutive days of a 28-day cycle. Repeat cycles every 2 to 6 weeks. (2.1) Provide supportive care, such as intravenous infusion fluids, antihyperuricemic treatment and alkalinization of urine throughout the 5 days of clofarabine injection administration to reduce the risk of tumor lysis and other adverse reactions. ( 2.1) Discontinue clofarabine injection if hy |
| Active ingredient(s) | CLOFARABINE |
| Route | INTRAVENOUS |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0da6764d-5fac-7e0f-ea3e-a5aee55a8b2d |