Fenofibrate
Fenofibrate is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Fenofibrate; Generic name: FENOFIBRATE; Drug class: Peroxisome Proliferator Receptor alpha Agonist [EPC].
| Brand name | Fenofibrate |
|---|---|
| Generic name | FENOFIBRATE |
| Drug class | Peroxisome Proliferator Receptor alpha Agonist [EPC] |
| Manufacturer | Cipla USA Inc., |
| Used for | INDICATIONS AND USAGE Treatment of Hypercholesterolemia Fenofibrate capsules, USP are indicated as adjunctive therapy to diet for the reduction of LDLC, total-C, Triglycerides and apo B in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Lipid altering agents should be used in addition to a diet restricted in saturated fat and cholesterol when response to diet and non-pharmacological interventions alone has been inadequate (see National Cholesterol Education Program [NCEP] Treatment Guidelines , below). Treatment of Hypertriglyceridemia Fenofibrate capsules, USP are also indicated as adjunctive therapy to diet for treatment of adult pati |
| Dosage | DOSAGE AND ADMINISTRATION Patients should be placed on an appropriate lipid-lowering diet before receiving fenofibrate capsules, and should continue this diet during treatment with fenofibrate capsules. Fenofibrate capsules should be given with meals, thereby optimizing the bioavailability of the medication. For the treatment of adult patients with primary hypercholesterolemia or mixed hyperlipidemia, the initial dose of fenofibrate capsules is 200 mg per day. For adult patients with hypertrigly |
| Warnings | WARNINGS Liver Function Fenofibrate capsules at doses equivalent to 134 mg to 200 mg fenofibrate per day has been associated with increases in serum transaminases [AST (SGOT) or ALT (SGPT)]. In a pooled analysis of 10 placebo controlled trials, increases to > 3 times the upper limit of normal occurred in 5.3% of patients taking fenofibrate versus 1.1% of patients treated with placebo. When transaminase determinations were followed either after discontinuation of treatment or during continued tre |
| Active ingredient(s) | FENOFIBRATE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=07d47c02-ab29-4ba9-aea0-96ffbd70c0ef |