FLUOROURACIL
FLUOROURACIL is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: FLUOROURACIL; Generic name: FLUOROURACIL; Drug class: Nucleoside Metabolic Inhibitor [EPC].
| Brand name | FLUOROURACIL |
|---|---|
| Generic name | FLUOROURACIL |
| Drug class | Nucleoside Metabolic Inhibitor [EPC] |
| Manufacturer | Eugia US LLC |
| Used for | 1 INDICATIONS AND USAGE Fluorouracil injection is indicated for the treatment of patients with: Fluorouracil injection is a nucleoside metabolic inhibitor indicated for the treatment of patients with Adenocarcinoma of the Colon and Rectum ( 1.1 ) Adenocarcinoma of the Breast ( 1.2 ) Gastric Adenocarcinoma ( 1.3 ) Pancreatic Adenocarcinoma ( 1.4 ) 1.1 Adenocarcinoma of the Colon and Rectum . 1.2 Adenocarcinoma of the Breast . 1.3 Gastric Adenocarcinoma . 1.4 Pancreatic Adenocarcinoma . |
| Dosage | 2 DOSAGE AND ADMINISTRATION Fluorouracil injection is recommended for administration either as an intravenous bolus or as an intravenous infusion. ( 2.2 ) See Full Prescribing Information for dose individualization ( 2.2 ) and dose modifications due to adverse reactions ( 2.7 ) See Full Prescribing Information for recommended doses of fluorouracil injection for adenocarcinoma of the colon and rectum ( 2.3 ) and for recommended doses of fluorouracil injection as a component of a chemotherapy regi |
| Warnings | WARNING: SERIOUS ADVERSE REACTIONS OR DEATH IN PATIENTS WITH COMPLETE DPD DEFICIENCY Increased Risk of Serious Adverse Reactions or Death in Patients with Complete DPD Deficiency Test patients for genetic variants of DPYD prior to initiating fluorouracil unless immediate treatment is necessary. Avoid use of fluorouracil in patients with certain homozygous or compound heterozygous DPYD variants that result in complete DPD deficiency [see Warnings and Precautions (5.1) ] . WARNING: SERIOUS ADVERSE |
| Active ingredient(s) | FLUOROURACIL |
| Route | INTRAVENOUS |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=199ef964-8a9b-403e-a2ae-759280b3d1d1 |