Ibutilide Fumarate
Ibutilide Fumarate is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Ibutilide Fumarate; Generic name: IBUTILIDE FUMARATE; Manufacturer: Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc..
| Brand name | Ibutilide Fumarate |
|---|---|
| Generic name | IBUTILIDE FUMARATE |
| Manufacturer | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. |
| Used for | INDICATIONS AND USAGE Ibutilide fumarate injection is indicated for the rapid conversion of atrial fibrillation or atrial flutter of recent onset to sinus rhythm. Patients with atrial arrhythmias of longer duration are less likely to respond to ibutilide fumarate. The effectiveness of ibutilide has not been determined in patients with arrhythmias of more than 90 days in duration. LIFE-THREATENING ARRHYTHMIAS—APPROPRIATE TREATMENT ENVIRONMENT Ibutilide fumarate can cause potentially fatal arrhythmias, particularly sustained polymorphic ventricular tachycardia, usually in association with QT prolongation (torsades de pointes), but sometimes without documented QT prolongation. In registration s |
| Dosage | DOSAGE AND ADMINISTRATION The recommended dose based on controlled trials (see CLINICAL STUDIES ) is outlined in the Table below. Ibutilide infusion should be stopped as soon as the presenting arrhythmia is terminated or in the event of sustained or nonsustained ventricular tachycardia, or marked prolongation of QT or QTc. Recommended Dose of Ibutilide Fumarate Injection Patient Weight Initial Infusion (over 10 minutes) Second Infusion 60 kg (132 lb) or more One vial (1 mg ibutilide fumarate) If |
| Warnings | WARNINGS Proarrhythmia Like other antiarrhythmic agents, ibutilide fumarate injection can induce or worsen ventricular arrhythmias in some patients. This may have potentially fatal consequences. Torsades de pointes, a polymorphic ventricular tachycardia that develops in the setting of a prolonged QT interval, may occur because of the effect ibutilide fumarate has on cardiac repolarization, but ibutilide fumarate can also cause polymorphic VT in the absence of excessive prolongation of the QT int |
| Active ingredient(s) | IBUTILIDE FUMARATE |
| Route | INTRAVENOUS |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0cf8724a-f0d1-4ce2-b7c1-cf5fac345fd0 |