Isotretinoin
Isotretinoin is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Isotretinoin; Generic name: ISOTRETINOIN; Drug class: Retinoid [EPC].
| Brand name | Isotretinoin |
|---|---|
| Generic name | ISOTRETINOIN |
| Drug class | Retinoid [EPC] |
| Manufacturer | Upsher-Smith Laboratories, LLC |
| Used for | 1 INDICATIONS AND USAGE Isotretinoin capsules are indicated for the treatment of severe recalcitrant nodular acne in non-pregnant patients 12 years of age and older with multiple inflammatory nodules with a diameter of 5 mm or greater. Because of significant adverse reactions associated with its use, isotretinoin capsules are reserved for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. Isotretinoin capsules are retinoids indicated for the treatment of severe recalcitrant nodular acne in non-pregnant patients 12 years of age and older with multiple inflammatory nodules with a diameter of 5 mm or greater. Because of significant ad |
| Dosage | 2 DOSAGE AND ADMINISTRATION Recommended dosage for isotretinoin capsules is 0.5 to 1 mg/kg/day given in two divided doses without regard to meals for 15 to 20 weeks ( 2.1 ) Adult patients with very severe disease (scarring, trunk involvement) may increase dosage to 2 mg/kg/day of isotretinoin capsules in divided doses. ( 2.1 ) Once daily dosing is not recommended. ( 2.1 ) If a dose of isotretinoin capsules is missed, just skip that dose. Do not take two doses of isotretinoin capsules at the same |
| Warnings | WARNING: EMBRYO-FETAL TOXICITY – CONTRAINDICATED IN PREGNANCY Isotretinoin capsules can cause severe life-threatening birth defects and is contraindicated in pregnancy. There is an extremely high risk that life-threatening birth defects will result if pregnancy occurs while taking any amount of isotretinoin capsules even for short periods of time. Potentially any fetus exposed during pregnancy can be affected. There are no accurate means of determining prenatally whether an exposed fetus has bee |
| Active ingredient(s) | ISOTRETINOIN |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=08529687-26b2-41e5-b6fb-35b4c0d891fe |