Labetalol HCL (LABETALOL HYDROCHLORIDE)
Labetalol HCL (LABETALOL HYDROCHLORIDE) is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Labetalol HCL; Generic name: LABETALOL HYDROCHLORIDE; Manufacturer: Bryant Ranch Prepack.
| Brand name | Labetalol HCL |
|---|---|
| Generic name | LABETALOL HYDROCHLORIDE |
| Manufacturer | Bryant Ranch Prepack |
| Used for | INDICATIONS AND USAGE Labetalol hydrochloride tablets, USP are indicated in the management of hypertension. Labetalol hydrochloride tablets, USP may be used alone or in combination with other antihypertensive agents, especially thiazide and loop diuretics. |
| Dosage | DOSAGE AND ADMINISTRATION DOSAGE MUST BE INDIVIDUALIZED. The recommended initial dosage is 100 mg twice daily whether used alone or added to a diuretic regimen. After 2 or 3 days, using standing blood pressure as an indicator, dosage may be titrated in increments of 100 mg b.i.d. every 2 or 3 days. The usual maintenance dosage of labetalol HCl is between 200 and 400 mg twice daily. Since the full antihypertensive effect of labetalol HCl is usually seen within the first 1 to 3 hours of the initia |
| Warnings | WARNINGS Hepatic Injury: Severe hepatocellular injury, confirmed by rechallenge in at least one case, occurs rarely with labetalol therapy.The hepatic injury is usually reversible, but hepatic necrosis and death have been reported. Injury has occurred after both short- and long-term treatment and may be slowly progressive despite minimal symptomatology. Similar hepatic events have been reported with a related research compound, dilevalol HCl, including two deaths. Dilevalol HCl is one of the fou |
| Active ingredient(s) | LABETALOL HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=06ff81fe-9226-49a7-aa5c-f52b059d7cab |