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Lidocaine and prilocaine

Lidocaine and prilocaine is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Lidocaine and prilocaine; Generic name: LIDOCAINE AND PRILOCAINE; Drug class: Amide Local Anesthetic [EPC].

Brand nameLidocaine and prilocaine
Generic nameLIDOCAINE AND PRILOCAINE
Drug classAmide Local Anesthetic [EPC]
ManufacturerViona Pharmaceuticals Inc
Used forINDICATIONS AND USAGE Lidocaine and prilocaine cream USP, (a eutectic mixture of lidocaine 2.5% and prilocaine 2.5%) is indicated as a topical anesthetic for use on: - normal intact skin for local analgesia. - genital mucous membranes for superficial minor surgery and as pretreatment for infiltration anesthesia. Lidocaine and prilocaine cream are not recommended in any clinical situation when penetration or migration beyond the tympanic membrane into the middle ear is possible because of the ototoxic effects observed in animal studies (see WARNINGS ).
DosageDOSAGE AND ADMINISTRATION Adult Patients-Intact Skin A thick layer of lidocaine and prilocaine cream is applied to intact skin and covered with an occlusive dressing (see INSTRUCTIONS FOR APPLICATION ). Minor Dermal Procedures For minor procedures such as intravenous cannulation and venipuncture, apply 2.5 grams of lidocaine and prilocaine cream (1/2 the 5 g tube) over 20 cm 2 to 25 cm 2 of skin surface for at least 1 hour. In controlled clinical trials using lidocaine and prilocaine cream, two
WarningsWARNINGS Application of lidocaine and prilocaine cream to larger areas or for longer times than those recommended could result in sufficient absorption of lidocaine and prilocaine resulting in serious adverse effects (see Individualization of Dose ). Patients treated with class III anti-arrhythmic drugs (e.g., amiodarone, bretylium, sotalol, dofetilide) should be under close surveillance and ECG monitoring considered, because cardiac effects may be additive. Studies in laboratory animals (guinea
Active ingredient(s)LIDOCAINE
RouteTOPICAL
Official labelhttps://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a3b26d3-7a32-4403-88ab-0924356b5214

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