Losartan Potassium and Hydrochlorothiazide
Losartan Potassium and Hydrochlorothiazide is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Losartan Potassium and Hydrochlorothiazide; Generic name: LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE; Drug class: Thiazide Diuretic [EPC].
| Brand name | Losartan Potassium and Hydrochlorothiazide |
|---|---|
| Generic name | LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE |
| Drug class | Thiazide Diuretic [EPC] |
| Manufacturer | Proficient Rx LP |
| Used for | INDICATIONS AND USAGE Hypertension Losartan potassium and hydrochlorothiazide tablets, USP are indicated for the treatment of hypertension. This fixed dose combination is not indicated for initial therapy of hypertension, except when the hypertension is severe enough that the value of achieving prompt blood pressure control exceeds the risk of initiating combination therapy in these patients (see CLINICAL PHARMACOLOGY, Pharmacodynamics and Clinical Effects , and DOSAGE AND ADMINISTRATION ). Hypertensive Patients with Left Ventricular Hypertrophy Losartan potassium and hydrochlorothiazide tablets, USP are indicated to reduce the risk of stroke in patients with hypertension and left ventricula |
| Dosage | DOSAGE AND ADMINISTRATION Hypertension Dosing must be individualized. The usual starting dose of losartan is 50 mg once daily, with 25 mg recommended for patients with intravascular volume depletion (e.g., patients treated with diuretics) (see WARNINGS, Hypotension - Volume-Depleted Patients ) and patients with a history of hepatic impairment (see WARNINGS, Impaired Hepatic Function ). Losartan can be administered once or twice daily at total daily doses of 25 to 100 mg. If the antihypertensive |
| Warnings | WARNINGS Fetal Toxicity Pregnancy Category D Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue losartan potassium and hyd |
| Active ingredient(s) | HYDROCHLOROTHIAZIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=198d5151-7982-4639-9fe1-6573a4529348 |