Lubiprostone
Lubiprostone is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Lubiprostone; Generic name: LUBIPROSTONE; Drug class: Chloride Channel Activator [EPC].
| Brand name | Lubiprostone |
|---|---|
| Generic name | LUBIPROSTONE |
| Drug class | Chloride Channel Activator [EPC] |
| Manufacturer | Northstar Rx LLC |
| Used for | 1. INDICATIONS AND USAGE Lubiprostone capsules is a chloride channel activator indicated for the treatment of: chronic idiopathic constipation (CIC) in adults. (1.1) opioid-induced constipation (OIC) in adult patients with chronic, non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation. (1.2) o Limitations of Use: Effectiveness of lubiprostone capsules in the treatment of OIC in patients taking diphenylheptane opioids (e.g., methadone) has not been established. (1.2, 7.1) irritable bowel syndrome with constipation (IBS-C) in women ≥18 years old. (1.3) 1.1 Chronic Idiopathic Constipatio |
| Dosage | 2. DOSAGE AND ADMINISTRATION Recommended Dosage (2.1) CIC and OIC: 24 mcg twice daily. IBS-C: 8 mcg twice daily. See full prescribing information for dosage adjustment by indication and degree of hepatic impairment. Administration Instructions (2.2) Swallow capsules whole and do not break apart or chew, Take capsules with food and water, Assess periodically the need for continuous therapy. 2.1 Recommended Dosage The recommended oral dosage of lubiprostone capsules by indication and adjustments f |
| Active ingredient(s) | LUBIPROSTONE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1626ac65-ea12-421b-9780-bfdb50a39e1a |