METFORMIN HYDROCHLORIDE
METFORMIN HYDROCHLORIDE is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: METFORMIN HYDROCHLORIDE; Generic name: METFORMIN HYDROCHLORIDE; Manufacturer: Laurus Labs Limited.
| Brand name | METFORMIN HYDROCHLORIDE |
|---|---|
| Generic name | METFORMIN HYDROCHLORIDE |
| Manufacturer | Laurus Labs Limited |
| Used for | 1 INDICATIONS AND USAGE Metformin hydrochloride extended-release tablets is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. Metformin hydrochloride extended-release tablets is a biguanide indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. (1) |
| Dosage | 2 DOSAGE AND ADMINISTRATION Recommended Dosage in Adults and Pediatric Patients Aged 10 Years and Older: • Swallow metformin hydrochloride extended-release tablets whole and never crush, cut or chew ( 2.2 ) • Starting dosage: 500 mg orally once daily with the evening meal ( 2.2 ) • Increase the dosage in increments of 500 mg weekly, up to a maximum dosage of 2,000 mg once daily with the evening meal ( 2.2 ) • Patients receiving metformin hydrochloride immediate-release tablets may be switched to |
| Warnings | WARNING: LACTIC ACIDOSIS Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias. The onset of metformin-associated lactic acidosis is often subtle, accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, somnolence, and abdominal pain. Metformin-associated lactic acidosis was characterized by elevated blood lactate levels (>5 mmol/Liter), anion gap acidosis (without evidence of |
| Active ingredient(s) | METFORMIN HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0e7b02cc-2ddc-4394-a80c-128e6452d697 |