METFORMIN HYDROCHLORIDE
METFORMIN HYDROCHLORIDE is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: METFORMIN HYDROCHLORIDE; Generic name: METFORMIN HYDROCHLORIDE; Manufacturer: Lupin Pharmaceuticals, Inc..
| Brand name | METFORMIN HYDROCHLORIDE |
|---|---|
| Generic name | METFORMIN HYDROCHLORIDE |
| Manufacturer | Lupin Pharmaceuticals, Inc. |
| Used for | 1 INDICATIONS AND USAGE Metformin hydrochloride extended-release tablet is a biguanide indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. ( 1 ) Metformin hydrochloride extended-release tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. |
| Dosage | 2 DOSAGE AND ADMINISTRATION Starting dose: 500 mg orally once daily with the evening meal ( 2.1 ) Increase the dose in increments of 500 mg every 1 to 2 weeks, up to a maximum of 2,000 mg once daily with the evening meal. ( 2.1 ) Patients receiving metformin hydrochloride (HCl) tablets may be switched to metformin hydrochloride extended-release tablets once daily at the same total daily dose, up to 2,000 mg once daily. ( 2.1 ) Swallow metformin hydrochloride extended-release tablets whole and ne |
| Warnings | WARNING: LACTIC ACIDOSIS WARNING: LACTIC ACIDOSIS See full prescribing information for complete boxed warning Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias. Symptoms included malaise, myalgias, respiratory distress, somnolence, and abdominal pain. Laboratory abnormalities included elevated blood lactate levels, anion gap acidosis, increased lactate/pyruvate ratio; and metformin plasma levels generally |
| Active ingredient(s) | METFORMIN HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1200ea71-8a9e-4e49-bb77-7d9fe0d84ae7 |