NALTREXONE HYDROCHLORIDE
NALTREXONE HYDROCHLORIDE is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: NALTREXONE HYDROCHLORIDE; Generic name: NALTREXONE HYDROCHLORIDE; Manufacturer: SpecGx LLC.
| Brand name | NALTREXONE HYDROCHLORIDE |
|---|---|
| Generic name | NALTREXONE HYDROCHLORIDE |
| Manufacturer | SpecGx LLC |
| Used for | INDICATIONS AND USAGE Naltrexone hydrochloride tablets are indicated in the treatment of alcohol dependence and for the blockade of the effects of exogenously administered opioids. Naltrexone hydrochloride tablets have not been shown to provide any therapeutic benefit except as part of an appropriate plan of management for the addictions. |
| Dosage | DOSAGE AND ADMINISTRATION To reduce the risk of precipitated withdrawal in patients dependent on opioids, or exacerbation of a preexisting subclinical withdrawal syndrome, opioid-dependent patients, including those being treated for alcohol dependence, should be opioid-free (including tramadol) before starting naltrexone treatment. An opioid-free interval of a minimum of 7 to 10 days is recommended for patients previously dependent on short-acting opioids. Switching from Buprenorphine, Buprenorp |
| Warnings | WARNINGS Vulnerability to Opioid Overdose After opioid detoxification, patients are likely to have reduced tolerance to opioids. As the blockade of exogenous opioids provided by naltrexone wanes and eventually dissipates completely, patients who have been treated with naltrexone may respond to lower doses of opioids than previously used, just as they would shortly after completing detoxification. This could result in potentially life-threatening opioid intoxication (respiratory compromise or arr |
| Active ingredient(s) | NALTREXONE HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=06ff2d5a-e62b-4fa4-bbdb-01938535bc65 |