Nicardipine Hydrochloride
Nicardipine Hydrochloride is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Nicardipine Hydrochloride; Generic name: NICARDIPINE HYDROCHLORIDE; Manufacturer: PuraCap Laboratories LLC dba Blu Pharmaceuticals.
| Brand name | Nicardipine Hydrochloride |
|---|---|
| Generic name | NICARDIPINE HYDROCHLORIDE |
| Manufacturer | PuraCap Laboratories LLC dba Blu Pharmaceuticals |
| Used for | INDICATIONS AND USAGE I. Stable Angina Nicardipine hydrochloride capsules are indicated for the management of patients with chronic stable angina (effort-associated angina). Nicardipine hydrochloride capsules may be used alone or in combination with beta-blockers. II. Hypertension Nicardipine hydrochloride capsules are indicated for the treatment of hypertension. Nicardipine hydrochloride capsules may be used alone or in combination with other antihypertensive drugs. In administering nicardipine hydrochloride it is important to be aware of the relatively large peak to trough differences in blood pressure effect (See DOSAGE AND ADMINISTRATION ). |
| Dosage | DOSAGE AND ADMINISTRATION Angina The dose should be individually titrated for each patient beginning with 20 mg three times daily. Doses in the range of 20 to 40 mg three times a day have been shown to be effective. At least 3 days should be allowed before increasing the nicardipine hydrochloride capsuels dose to ensure achievement of steady-state plasma drug concentrations. Concomitant Use With Other Antianginal Agents Sublingual NTG may be taken as required to abort acute anginal attacks durin |
| Warnings | WARNINGS Increased Angina About 7% of patients in short-term, placebo-controlled angina trials have developed increased frequency, duration or severity of angina on starting nicardipine hydrochloride capsules or at the time of dosage increases, compared with 4% of patients on placebo. Comparisons with beta-blockers also show a greater frequency of increased angina, 4% vs 1%. The mechanism of this effect has not been established (see ADVERSE REACTIONS ). Use in Patients With Congestive Heart Fail |
| Active ingredient(s) | NICARDIPINE HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=065efabf-8c7d-4dd5-aef2-700c2eca399d |