Pacerone (AMIODARONE HYDROCHLORIDE)
Pacerone (AMIODARONE HYDROCHLORIDE) is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Pacerone; Generic name: AMIODARONE HYDROCHLORIDE; Manufacturer: Aphena Pharma Solutions - Tennessee, LLC.
| Brand name | Pacerone |
|---|---|
| Generic name | AMIODARONE HYDROCHLORIDE |
| Manufacturer | Aphena Pharma Solutions - Tennessee, LLC |
| Used for | 1 INDICATIONS AND USAGE Pacerone is indicated for the treatment of documented, life-threatening recurrent ventricular fibrillation and life-threatening recurrent hemodynamically unstable tachycardia in adults who have not responded to adequate doses of other available antiarrhythmics or when alternative agents cannot be tolerated. Pacerone is an antiarrhythmic indicated for: Recurrent ventricular fibrillation. ( 1 ) Recurrent hemodynamically unstable ventricular tachycardia. ( 1 ) |
| Dosage | 2 DOSAGE AND ADMINISTRATION Dosage must be individualized based on severity of arrhythmia and response. Use the lowest effective dose. Obtain baseline chest x-ray, pulmonary function tests, thyroid function tests, and liver aminotransferases. Correct hypokalemia, hypomagnesemia, and hypocalcemia before initiating treatment. Initiate treatment with a loading dose of 800 to 1600 mg/day until initial therapeutic response occurs (usually 1 to 3 weeks). Once adequate arrhythmia control is achieved, o |
| Warnings | WARNING: PULMONARY, HEPATIC and CARDIAC TOXICITY Pacerone is intended for use only in patients with the indicated life-threatening arrhythmias because its use is accompanied by substantial toxicity [see Indications and Usage (1) ] . Pacerone can cause pulmonary toxicity (hypersensitivity pneumonitis or interstitial/alveolar pneumonitis) that has resulted in clinically manifest disease at rates as high as 17% in some series of patients. Pulmonary toxicity has been fatal about 10% of the time . Ob |
| Active ingredient(s) | AMIODARONE HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=02f4a736-63ed-4ad4-a1f1-b21a71e928bd |