Pemetrexed (PEMETREXED DISODIUM)
Pemetrexed (PEMETREXED DISODIUM) is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Pemetrexed; Generic name: PEMETREXED DISODIUM; Manufacturer: BluePoint Laboratories.
| Brand name | Pemetrexed |
|---|---|
| Generic name | PEMETREXED DISODIUM |
| Manufacturer | BluePoint Laboratories |
| Used for | 1 INDICATIONS AND USAGE Pemetrexed for injection is a folate analog metabolic inhibitor indicated: in combination with pembrolizumab and platinum chemotherapy, for the initial treatment of patients with metastatic non-squamous non-small cell lung cancer (NSCLC), with no EGFR or ALK genomic tumor aberrations. ( 1.1 ) in combination with cisplatin for the initial treatment of patients with locally advanced or metastatic, non-squamous NSCLC. ( 1.1 ) as a single agent for the maintenance treatment of patients with locally advanced or metastatic, non-squamous NSCLC whose disease has not progressed after four cycles of platinum-based first-line chemotherapy. ( 1.1 ) as a single agent for the treat |
| Dosage | 2 DOSAGE AND ADMINISTRATION The recommended dose of pemetrexed for injection administered with pembrolizumab and platinum chemotherapy in patients with a creatinine clearance (calculated by Cockcroft-Gault equation) of 45 mL/min or greater is 500 mg/m 2 as an intravenous infusion over 10 minutes, administered after pembrolizumab and prior to platinum chemotherapy, on Day 1 of each 21-day cycle. ( 2.1 ) The recommended dose of pemetrexed for injection, administered as a single agent or with cispl |
| Active ingredient(s) | PEMETREXED DISODIUM |
| Route | INTRAVENOUS |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=14974d4e-2f01-4e02-aea2-c28b3ca0781c |