Pilocarpine Hydrochloride
Pilocarpine Hydrochloride is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Pilocarpine Hydrochloride; Generic name: PILOCARPINE HYDROCHLORIDE; Manufacturer: Bryant Ranch Prepack.
| Brand name | Pilocarpine Hydrochloride |
|---|---|
| Generic name | PILOCARPINE HYDROCHLORIDE |
| Manufacturer | Bryant Ranch Prepack |
| Used for | INDICATIONS AND USAGE: Pilocarpine hydrochloride tablets, USP are indicated for 1) the treatment of symptoms of dry mouth from salivary gland hypofunction caused by radiotherapy for cancer of the head and neck; and 2) the treatment of symptoms of dry mouth in patients with Sjogren's syndrome. |
| Dosage | DOSAGE AND ADMINISTRATION: Regardless of the indication, the starting dose in patients with moderate hepatic impairment should be 5 mg twice daily, followed by adjustment based on therapeutic response and tolerability. Patients with mild hepatic insufficiency do not require dosage reductions. The use of pilocarpine in patients with severe hepatic insufficiency is not recommended. If needed, refer to the Hepatic Insufficiency subsection of the Precautions section of this label for definitions of |
| Warnings | WARNINGS: Cardiovascular Disease: Patients with significant cardiovascular disease may be unable to compensate for transient changes in hemodynamics or rhythm induced by pilocarpine. Pulmonary edema has been reported as a complication of pilocarpine toxicity from high ocular doses given for acute angle-closure glaucoma. Pilocarpine should be administered with caution in and under close medical supervision of patients with significant cardiovascular disease. Ocular: Ocular formulations of pilocar |
| Active ingredient(s) | PILOCARPINE HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=06c054af-62b4-4373-813a-9bb2e5c92316 |