posfrea (PALONOSETRON)
posfrea (PALONOSETRON) is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: posfrea; Generic name: PALONOSETRON; Manufacturer: Avyxa Pharma, LLC.
| Brand name | posfrea |
|---|---|
| Generic name | PALONOSETRON |
| Manufacturer | Avyxa Pharma, LLC |
| Used for | 1 INDICATIONS AND USAGE POSFREA is indicated in adults for prevention of: acute and delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy (MEC). acute nausea and vomiting associated with initial and repeat courses highly emetogenic cancer chemotherapy (HEC). postoperative nausea and vomiting (PONV) for up to 24 hours following surgery. Efficacy beyond 24 hours has not been demonstrated. As with other antiemetics, routine prophylaxis is not recommended in patients in whom there is little expectation that nausea and/or vomiting will occur postoperatively. In patients where nausea and vomiting must be avoided during the postoperative |
| Dosage | 2 DOSAGE AND ADMINISTRATION Chemotherapy-Induced Nausea and Vomiting (CINV) ( 2.1 ) *Note different dosing units in pediatrics Age Dose* Infusion Time Adults 0.25 mg as a single dose Infuse over 30 seconds beginning approximately 30 minutes before the start of chemotherapy Pediatrics (1 month to less than 17 years) 20 micrograms per kilogram (maximum 1.5 mg) as a single dose Infuse over 15 minutes beginning approximately 30 minutes before the start of chemotherapy Postoperative Nausea and Vomiti |
| Active ingredient(s) | PALONOSETRON HYDROCHLORIDE |
| Route | INTRAVENOUS |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=13a201ba-c86d-48c5-a0e1-a3e0b4e6a2a7 |