Sevoflurane, (Volatile for Inhalation) (SEVOFLURANE)
Sevoflurane, (Volatile for Inhalation) (SEVOFLURANE) is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Sevoflurane, (Volatile for Inhalation); Generic name: SEVOFLURANE; Drug class: General Anesthetic [EPC].
| Brand name | Sevoflurane, (Volatile for Inhalation) |
|---|---|
| Generic name | SEVOFLURANE |
| Drug class | General Anesthetic [EPC] |
| Manufacturer | Mullan Pharmaceutical Inc. |
| Used for | INDICATIONS AND USAGE Sevoflurane is indicated for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery. Sevoflurane should be administered only by persons trained in the administration of general anesthesia. Facilities for maintenance of a patent airway, artificial ventilation, oxygen enrichment, and circulatory resuscitation must be immediately available. Since level of anesthesia may be altered rapidly, only vaporizers producing predictable concentrations of sevoflurane should be used. |
| Dosage | DOSAGE AND ADMINISTRATION The concentration of sevoflurane being delivered from a vaporizer should be known. This may be accomplished by using a vaporizer calibrated specifically for sevoflurane. The administration of general anesthesia must be individualized based on the patient's response. Replacement of Desiccated CO 2 Absorbents When a clinician suspects that the CO 2 absorbent may be desiccated, it should be replaced. The exothermic reaction that occurs with sevoflurane and CO 2 absorbents |
| Warnings | WARNINGS Risk of Renal Injury Although data from controlled clinical studies at low flow rates are limited, findings taken from patient and animal studies suggest that there is a potential for renal injury which is presumed due to Compound A. Animal and human studies demonstrate that sevoflurane administered for more than 2 MAC ∙ hours and at fresh gas flow rates of < 2 L/min may be associated with proteinuria and glycosuria. While a level of Compound A exposure at which clinical nephrotoxicity |
| Active ingredient(s) | SEVOFLURANE |
| Route | RESPIRATORY (INHALATION) |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0ca6da3a-6a18-400d-8c49-08a5534b025f |