Sotalol Hydrochloride
Sotalol Hydrochloride is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Sotalol Hydrochloride; Generic name: SOTALOL HYDROCHLORIDE; Manufacturer: Proficient Rx LP.
| Brand name | Sotalol Hydrochloride |
|---|---|
| Generic name | SOTALOL HYDROCHLORIDE |
| Manufacturer | Proficient Rx LP |
| Used for | 1 INDICATIONS AND USAGE Sotalol hydrochloride tablets are an antiarrhythmic indicated for: • the treatment of life-threatening ventricular arrhythmias ( 1.1 ) • the maintenance of normal sinus rhythm in patients with atrial fibrillation or flutter (AFIB/AFL) ( 1.2 ) Limitations of Use • Sotalol hydrochloride tablets have not been shown to enhance survival in patients with life-threatening ventricular arrhythmias ( 1.1 ) • Avoid use in patients with minimally symptomatic or easily reversible AFIB/AFL ( 1.2 ) 1.1 Life-Threatening Ventricular Arrhythmias Sotalol hydrochloride tablets are indicated for the treatment of documented, life-threatening ventricular arrhythmias, such as sustained ventr |
| Dosage | 2 DOSAGE AND ADMINISTRATION • Sotalol hydrochloride tablets: Initial dosage in adults is 80 mg twice daily. Increase the dose as needed in increments of 80 mg/day, every 3 days to a maximum 320 mg total daily dose ( 2.2 ) • Pediatrics: Dosage depends on age ( 2.4 ) 2.1 General Safety Measures for Initiation of Oral Sotalol Therapy Withdraw other antiarrhythmic therapy before starting sotalol hydrochloride tablets and monitor for a minimum of 2 to 3 plasma half-lives prior to initiating sotalol h |
| Warnings | WARNING: LIFE-THREATENING PROARRHYTHMIA To minimize the risk of drug-induced arrhythmia, initiate or reinitiate oral sotalol in a facility that can provide cardiac resuscitation and continuous electrocardiographic monitoring. Sotalol can cause life-threatening ventricular tachycardia associated with QT interval prolongation. If the QT interval prolongs to 500 msec or greater, reduce the dose, lengthen the dosing interval, or discontinue the drug. Calculate creatinine clearance to determine appro |
| Active ingredient(s) | SOTALOL HYDROCHLORIDE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=10b7b81d-9ce7-4025-8559-fdfa41c8b146 |