Tacrolimus
Tacrolimus is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Tacrolimus; Generic name: TACROLIMUS; Manufacturer: Major Pharmaceuticals.
| Brand name | Tacrolimus |
|---|---|
| Generic name | TACROLIMUS |
| Manufacturer | Major Pharmaceuticals |
| Used for | 1 INDICATIONS AND USAGE Tacrolimus capsule is a calcineurin-inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in adult patients receiving allogeneic liver, kidney, or heart transplants, and pediatric patients receiving allogeneic liver transplants in combination with other immunosuppressants. ( 1.1 ) 1.1 Prophylaxis of Organ Rejection in Kidney, Liver or Heart Transplant Tacrolimus capsules are indicated for the prophylaxis of organ rejection, in adult patients receiving allogeneic kidney transplant [see Clinical Studies ( 14.1 )] , liver transplant [see Clinical Studies ( 14.2 )] , heart transplant [ see Clinical Studies ( 14.3 )] , and pediatric patients receivin |
| Dosage | 2 DOSAGE AND ADMINISTRATION Intravenous (IV) use recommended for patients who cannot tolerate oralformulations (capsules). ( 2.1 , 2.2) • Administer capsules consistently with or without food.( 2.1) • Therapeutic drug monitoring is recommended. ( 2.1 , 2.6 ) • Avoid eating grapefruit or drinking grapefruit juice. (2.1 ) • See dosage adjustments for African-American patients (2.2) , hepatic and renal impaired. ( 2.4 , 2.5 ) • For complete dosing information, see Full Prescribing Information. ADUL |
| Warnings | WARNING: MALIGNANCIES AND SERIOUS INFECTIONS • Increased risk for developing serious infections and malignancies with tacrolimus or other immunosuppressants that may lead to hospitalization or death. ( 5.1 , 5.2 ) WARNING: MALIGNANCIES AND SERIOUS INFECTIONS See full prescribing information for complete boxed warning . • Increased risk for developing serious infections and malignancies with tacrolimus or other immunosuppressants that may lead to hospitalization or death. ( 5.1 , 5.2 ) |
| Active ingredient(s) | TACROLIMUS |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0addf3f5-9bd5-4ef3-8c7f-52be20c16cf9 |