Tenofovir Disoproxil Fumarate
Tenofovir Disoproxil Fumarate is one of 8,063 medications in the MedPlain dataset. Key details — Brand name: Tenofovir Disoproxil Fumarate; Generic name: TENOFOVIR DISOPROXIL FUMARATE; Manufacturer: Bryant Ranch Prepack.
| Brand name | Tenofovir Disoproxil Fumarate |
|---|---|
| Generic name | TENOFOVIR DISOPROXIL FUMARATE |
| Manufacturer | Bryant Ranch Prepack |
| Used for | 1 INDICATIONS AND USAGE Tenofovir disoproxil fumarate tablets are a nucleotide analog HIV-1 reverse transcriptase inhibitor and an HBV reverse transcriptase inhibitor and is indicated: • in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older weighing at least 10 kg. ( 1.1 ) • for the treatment of chronic hepatitis B in adults and pediatric patients 12 years and older. ( 1.2 ) 1.1 HIV-1 Infection Tenofovir disoproxil fumarate tablets are indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and pediatric patients 2 yea |
| Dosage | 2 DOSAGE AND ADMINISTRATION • Testing: Prior to or when initiating tenofovir disoproxil fumarate tablets test for hepatitis B virus infection and HIV-1 infection. Prior to initiation and during use of tenofovir disoproxil fumarate, on a clinically appropriate schedule, assess serum creatinine, estimated creatinine clearance, urine glucose, and urine protein in all patients. In patients with chronic kidney disease, also assess serum phosphorous. ( 2.1 ) • Recommended tablet dosage in adults and p |
| Warnings | WARNING: POSTTREATMENT ACUTE EXACERBATION OF HEPATITIS B Severe acute exacerbations of hepatitis B virus (HBV) have been reported in HBV-infected patients who have discontinued anti-hepatitis B therapy, including tenofovir disoproxil fumarate. Hepatic function should be monitored closely with both clinical and laboratory follow-up for at least several months in HBV-infected patients who discontinue anti-hepatitis B therapy, including tenofovir disoproxil fumarate. If appropriate, resumption of a |
| Active ingredient(s) | TENOFOVIR DISOPROXIL FUMARATE |
| Route | ORAL |
| Official label | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=18285dda-d63f-4f0e-821f-a4f2df335c35 |