A Computational Framework for Lymph Node Physiology — NSF Award to University of Notre Dame (IN, $470,116)
Lymph nodes are vital components of the immune and lymphatic systems, playing a key role in filtering lymphatic fluid, facilitating immune cell transfer, and regulating protein content in lymph. This project aims to develop a novel mathematical model and computational framework for lymph node dynamics, capturing both l
| Award title | A Computational Framework for Lymph Node Physiology |
|---|---|
| Award ID | 2602215 |
| Awardee | University of Notre Dame |
| City | NOTRE DAME |
| State | IN |
| Amount obligated | $470,116 |
| Principal investigator | Martina Bukac |
| Program | MATHEMATICAL BIOLOGY |
| Start date | 06/01/2026 |
| Abstract | Lymph nodes are vital components of the immune and lymphatic systems, playing a key role in filtering lymphatic fluid, facilitating immune cell transfer, and regulating protein content in lymph. This project aims to develop a novel mathematical model and computational framework for lymph node dynamics, capturing both lymph flow and the elastic deformation of the node, which remains largely unexplored in current models. By quantifying key parameters and processes governing these dynamics under va |
| Source | NSF Awards |
$799/mo
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