A Modular Toolset for Imaging Cellular Metabolites Using Fluorogenic RNA Riboswitches — NSF Award to University of Massachusetts A
Metabolites such as sugar and fatty acids are essential for maintaining human health because they influence energy supply, growth, and cell signaling. Abnormal metabolic changes can lead to diseases such as diabetes, cancer, and heart conditions. Detecting metabolites in living systems in real-time is crucial, but conv
| Award title | A Modular Toolset for Imaging Cellular Metabolites Using Fluorogenic RNA Riboswitches |
|---|---|
| Award ID | 2435059 |
| Awardee | University of Massachusetts Amherst |
| City | AMHERST |
| State | MA |
| Amount obligated | $401,490 |
| Principal investigator | Mingxu You |
| Program | BIOSENS-Biosensing |
| Start date | 05/15/2025 |
| Abstract | Metabolites such as sugar and fatty acids are essential for maintaining human health because they influence energy supply, growth, and cell signaling. Abnormal metabolic changes can lead to diseases such as diabetes, cancer, and heart conditions. Detecting metabolites in living systems in real-time is crucial, but conventional methods require obtaining and destroying samples, which means they can't be used to measure metabolites in individual cells. This project addresses the gap by developing f |
| Source | NSF Awards |
$799/mo
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