BRING-SynBio: Dynamic cooperative binders for endogenously gated cellular control — NSF Award to University of Chicago (IL, $300,0
Cells sense and respond to their environments. Immune system cells sense and respond to viruses, bacteria, and even cancer cells. Most sense and response circuits involve several intermediate molecules acting as a cascade. This takes time and makes it difficult to engineer these circuits to respond to new inputs or to
| Award title | BRING-SynBio: Dynamic cooperative binders for endogenously gated cellular control |
|---|---|
| Award ID | 2514164 |
| Awardee | University of Chicago |
| City | CHICAGO |
| State | IL |
| Amount obligated | $300,000 |
| Principal investigator | Bryan Dickinson |
| Program | Cellular & Biochem Engineering |
| Start date | 10/01/2025 |
| Abstract | Cells sense and respond to their environments. Immune system cells sense and respond to viruses, bacteria, and even cancer cells. Most sense and response circuits involve several intermediate molecules acting as a cascade. This takes time and makes it difficult to engineer these circuits to respond to new inputs or to generate new responses. Existing circuits often overlap and interact. This makes efforts to modify them subject to possible negative side effects. To avoid these problems, it is pr |
| Source | NSF Awards |
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