BRING-SynBio: Erythritol-Driven and Spatiotemporal-Controlled Probiotics for Precise Deliv — NSF Award to Texas A&M Engineering Ex
Immunoglobulin G (IgG) is a type of antibody. It is primarily active in controlling infection in body tissues. It actively binds viruses, bacteria, and fungi. Nanobodies (Nbs) are fragments of IgG. Some nanobodies exhibit anti-cancer activity. Bacteria can be modified to produce Nbs and one of these, E. coli Nissle 191
| Award title | BRING-SynBio: Erythritol-Driven and Spatiotemporal-Controlled Probiotics for Precise Deliv |
|---|---|
| Award ID | 2514387 |
| Awardee | Texas A&M Engineering Experiment Station |
| City | COLLEGE STATION |
| State | TX |
| Amount obligated | $300,000 |
| Principal investigator | Qing Sun |
| Program | Cellular & Biochem Engineering |
| Start date | 09/01/2025 |
| Abstract | Immunoglobulin G (IgG) is a type of antibody. It is primarily active in controlling infection in body tissues. It actively binds viruses, bacteria, and fungi. Nanobodies (Nbs) are fragments of IgG. Some nanobodies exhibit anti-cancer activity. Bacteria can be modified to produce Nbs and one of these, E. coli Nissle 1917 (EcN), has been shown to selectively colonize tumor tissue. This project will develop two gene circuits in EcN. The first will sense signals in the tumor microenvironment and res |
| Source | NSF Awards |
$799/mo
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