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CAREER: Advancing Precision Biomimetic Nanodelivery for Neurovascular Inflammation — NSF Award to Arizona State University (AZ, $5

Inflammation of the brain plays a major role in diseases such as stroke and dementia. Delivering medicines to the brain is difficult because often they do not reach damaged brain tissues. This CAREER project will produce biomimetic nanoparticles that have molecules specifically targeting brain blood vessels. The projec

Award titleCAREER: Advancing Precision Biomimetic Nanodelivery for Neurovascular Inflammation
Award ID2544114
AwardeeArizona State University
CitySCOTTSDALE
StateAZ
Amount obligated$561,273
Principal investigatorKuei-Chun Wang
ProgramNanoscale Interactions Program
Start date05/01/2026
AbstractInflammation of the brain plays a major role in diseases such as stroke and dementia. Delivering medicines to the brain is difficult because often they do not reach damaged brain tissues. This CAREER project will produce biomimetic nanoparticles that have molecules specifically targeting brain blood vessels. The project will determine how the nanoparticles adhere to and cross inflamed brain blood vessels in disease-mimicking models. The project will integrate nanotechnology, bioengineering, vasc
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