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CAREER: Bioelectronically programmable scaffolds for controlling ovarian follicle growth d — NSF Award to Washington University (M

The functional cells in female ovaries are follicles, which are spherical aggregates of cells containing an immature egg. Follicles cannot be replenished, so the total number declines as some follicles are selected for growth every month. The remaining follicles remain dormant to preserve reproductive function over sev

Award titleCAREER: Bioelectronically programmable scaffolds for controlling ovarian follicle growth d
Award ID2443128
AwardeeWashington University
CitySAINT LOUIS
StateMO
Amount obligated$629,999
Principal investigatorAlexandra Rutz
ProgramEngineering of Biomed Systems
Start date05/01/2025
AbstractThe functional cells in female ovaries are follicles, which are spherical aggregates of cells containing an immature egg. Follicles cannot be replenished, so the total number declines as some follicles are selected for growth every month. The remaining follicles remain dormant to preserve reproductive function over several decades. The mechanisms that determine which follicles are selected for growth and which remain dormant is poorly understood. A better understanding of these mechanisms could
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