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CAREER: Creating and evolving antibodies from scratch in yeast — NSF Award to Georgia Tech Research Corporation (GA, $647,941)

Antibodies are key proteins of the immune system that help fight disease. In people, immune cells called B cells create antibodies and then evolves them. B cells take months to do this, which makes it difficult to study antibody creation and evolution. This CAREER project will design a method to create and evolve antib

Award titleCAREER: Creating and evolving antibodies from scratch in yeast
Award ID2542524
AwardeeGeorgia Tech Research Corporation
CityATLANTA
StateGA
Amount obligated$647,941
Principal investigatorJohn Blazeck
ProgramCellular & Biochem Engineering
Start date06/01/2026
AbstractAntibodies are key proteins of the immune system that help fight disease. In people, immune cells called B cells create antibodies and then evolves them. B cells take months to do this, which makes it difficult to study antibody creation and evolution. This CAREER project will design a method to create and evolve antibodies “from scratch” in yeast, which will open new avenues for exploring antibody creation, evolution, and function. The results of the project will provide insights into the formu
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