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CAREER: Defining kinase-driven cellular response networks using single-cell genomics — NSF Award to Columbia University (NY, $542,

How a cell responds to stress is critical to its performance in biomedical applications. Modifying the response can dramatically improve treatment outcomes. For example, altering the response to chemotherapy could inhibit or reverse tumor growth. Altering the immune system response could reduce the need for vaccine dev

Award titleCAREER: Defining kinase-driven cellular response networks using single-cell genomics
Award ID2146007
AwardeeColumbia University
CityNEW YORK
StateNY
Amount obligated$542,418
Principal investigatorJose McFaline-Figueroa
ProgramCellular & Biochem Engineering
Start date02/15/2022
AbstractHow a cell responds to stress is critical to its performance in biomedical applications. Modifying the response can dramatically improve treatment outcomes. For example, altering the response to chemotherapy could inhibit or reverse tumor growth. Altering the immune system response could reduce the need for vaccine development. Many of the key regulators of these responses are enzymes known as kinases. Several kinase inhibitors have proven successful in treating certain cancers. Utilizing genomi
SourceNSF Awards

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